Prevention and treatment of oxidative stress disorders by...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/26 (2006.01) A61K 31/00 (2006.01) A61K 31/10 (2006.01) A61K 31/70 (2006.01) A61K 31/7028 (2006.01) A61K 38/44 (2006.01) A61K 38/45 (2006.01) A61K 38/46 (2006.01) A61K 38/53 (2006.01)

Patent

CA 2470583

The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracellular levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracellular levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders.

D'une manière générale, l'invention concerne le traitement des troubles liés au stress oxydatif par administration d'une quantité pharmaceutiquement efficace d'un composé qui augmente les taux intracellulaires de glutathione ou les taux intracellulaires d'au moins une enzyme de détoxification de phase II dans un tissu animal. L'invention concerne également la protection d'un sujet contre les troubles liés au stress oxydatif par administration d'une quantité pharmaceutiquement efficace d'un composé qui augmente les taux intracellulaires de glutathione ou les taux intracellulaires d'au moins une enzyme de détoxification de phase II chez le sujet. L'invention concerne enfin une composition pharmaceutique utile pour le traitement des troubles liés au stress oxydatif.

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