Prevention and treatment of radiation dermatitis

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/72 (2006.01) A61K 8/44 (2006.01) A61K 8/64 (2006.01) A61Q 17/00 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2602612

Novel uses of a hydrogel composition comprising one or more electrolytes are disclosed Suitable electrolytes are sodium chloride, sodium phosphate and a sodium salt of ethylenediammetetracetic acid. The hydrogel composition can comprise a biocompatible polymer component and a protein component covalently crosslinked by the biocompatible polymer. The uses are in the manufacture of a medicament for the prophylaxis and treatment of radiation dermatitis. The medicament can be applied to a topical site before, during, and/or after exposure of the topical site to ionizing radiation.

La présente invention concerne de nouvelles utilisations d~une composition d~hydrogel qui comprend un ou plusieurs électrolytes. Des électrolytes appropriés sont le chlorure de sodium, le phosphate de sodium et un sel de sodium de l'acide éthylènediaminetétraacétique. La composition d~hydrogel peut comprendre un composant de polymère biocompatible et un composant protéique réticulé de manière covalente par le polymère biocompatible. La composition de la présente invention est utilisée dans la fabrication d~un médicament pour la prophylaxie et le traitement de la radiodermite. Le médicament peut être appliqué à un site topique avant, pendant et/ou après l~exposition du site topique à un rayonnement ionisant.

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