Prevention and treatment of synucleinopathic and...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2576672

The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha- synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.

L'invention concerne des agents et des méthodes de traitement améliorés de maladies associées aux maladies synucléinopathiques, notamment les corps de Lewy de l'alpha-synucléine dans le cerveau d'un patient. De telles méthodes consistent à administrer des agents induisant une réponse immunogène bénéfique contre le corps de Lewy. Les méthodes sont spécialement utiles pour un traitement prophylactique et thérapeutique de la maladie de Parkinson.

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