Prevention and treatment of synucleinopathic disease

Details Prevention and treatment of synucleinopathic disease Prevention and treatment of synucleinopathic disease

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61B 1/00 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2503561

The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha- synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.

Cette invention concerne des améliorations apportées à des agents et des méthodes servant au traitement de maladies associées à des maladies synucléopathiques, telles que les corps de Lewy d'alpha-synucléine dans le cerveau d'un patient. Ces méthodes consistent à administrer des agents qui induisent une réponse immunogène bénéfique contre le corps de Lewy. Ces méthodes sont particulièrement utiles pour le traitement prophylactique et thérapeutique de la maladie de Parkinson.

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