Prevention of irreversible aggregation of viable...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 1/04 (2006.01) C12N 1/14 (2006.01) C12N 11/04 (2006.01)

Patent

CA 2254431

A method and composition are described for preventing irreversible aggregation of viable microorganisms which exhibit aggregative activity upon drying. The method comprises dispersing the microorganisms in an aqueous polymer solution containing a water-soluble or water-dispersable low molecular weight polymer such that the polymer solution inhibits direct surface contact between the individual microorganisms. The polymer solution containing the dispersed microorganisms is then dried to form a dry continuous polymer matrix containing the dispersed microorganisms. This dry continuous polymer matrix is adapted to substantially totally dissolved within five minutes in cold or room temperature water and to thereby provide a reconstituted solution containing uniformly dispersed microorganisms.

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