G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/564 (2006.01) A01K 67/027 (2006.01) A61K 38/00 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2499477
This invention relates to identificatican of an autoantigen implicated in the development and progression of Sjögren's Syndrome (pSS); particularly to the disease modifying effect of creating a deficiency in the ICA69 autoantigen; and most particularly to development of diagnostic and therapeutic avenues, means for the differential diagnosis of pSS versus other autoimmune disease, e.g. Systemic lupus erythematosis (SLE), and procedures for immunotherapeutic treatment effective to alter the course and progression of pSS.
La présente invention a trait à l'identification d'un auto-antigène impliqué dans le développement et la progression du syndrome de Sjögren primaire, notamment à l'effet de modification de la maladie de création de carence dans l'auto-antigène ICA69, et plus particulièrement au développement de procédés de diagnostic et thérapeutiques, de moyens pour le diagnostic différentiel du syndrome de Sjögren primaire par rapport à une autre maladie auto-immune, par exemple, le Lupus érythémateux systémique, et des procédés pour un traitement immumothérapeutique efficace afin de modifier l'évolution et la progression du syndrome de Sjögren primaire.
Dosch Hans-Michael
Winer Shawn
Smart & Biggar
The Hospital For Sick Children Research Institute
LandOfFree
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