Prevention of surgical adhesions using selective cox-2...

Details Prevention of surgical adhesions using selective cox-2... Prevention of surgical adhesions using selective cox-2...

A - Human Necessities

61

K

A61K 31/415 (2006.01)

Patent

CA 2552137

The present invention provides a method for the minimization or prevention of adhesion formation during or following a surgical procedure. The method comprises administering to the patient in need thereof a therapeutically effective amount of at least one COX-2 inhibitor, wherein the COX-2 inhibitor is not nimesulide. The COX-2 inhibitor can be administered before, during, or after surgery. In a preferred embodiment, the COX-2 inhibitor is celecoxib, also known as Celebrex (Pfizer).

L'invention porte sur un procédé de réduction ou prévention de la formation d'adhérences pendant ou à la suite d'actes chirurgicaux. Le procédé consiste à administrer à un patient le nécessitant une quantité à effet thérapeutique d'au moins un inhibiteur du COX-2 différent d'un nimésulide. Ledit inhibiteur peut être administré avant, pendant ou après une opération. Dans l'exécution préférée l'inhibiteur du COX-2 est du célécoxibe, également connu sous l'appellation de Célébrex (Pfizer).

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