Preventive and/or remedial agent for disease attributable to...

Details Preventive and/or remedial agent for disease attributable to... Preventive and/or remedial agent for disease attributable to...

A - Human Necessities

61

K

A61K 31/426 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 43/00 (2006.01) C07D 277/34 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2457836

A preventive and/or remedy for diseases attributable to arteriosclerotic activity, such as ischemic heart diseases and acute coronary arterial syndrome, which contains as an active ingredient a compound represented by the following general formula (I): (I) or a pharmaceutically acceptable salt of the compound. It is a novel preventive and/or remedy for diseases attributable to arteriosclerotic activity and is more potent than known drugs. (In the formula, A represents a thiazolidinedione ring, etc.; -X- represents -O- or -S- ; =Y- represents =N- or =CR5-; R1, R2, R3, R4, R5, and R6 each independently represents hydrogen, etc.; n is an integer of 0 to 3; and the dotted line indicates that the linkage may be a double bond.)

La présente invention concerne un agent prophylactique et/ou curatif destiné aux maladies liées à l'activité de l'artériosclérose, telles que les cardiopathies ischémiques et le syndrome artériel coronarien aigu. Cet agent prophylactique et/ou curatif contient en tant qu'ingrédient actif un composé représenté par la formule (I) ou un sel pharmaceutiquement acceptable de ce composé. Cet agent prophylactique et/ou curatif pour les maladies induites par l'activité de l'artériosclérose est nouveau et plus puissant que les médicaments connus à ce jour. Dans la formule, A représente un anneau thiazolidinedione et autres; -X- représente -O- ou S- ; =Y- représente =N- ou =CR?5¿- ; R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ représentent indépendamment hydrogène et autres; n représente un entier compris entre 0 et 3; et la ligne en pointillé indique que la liaison peut être une liaison double. Formule (I)

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