Preventive or remedy for diseases caused by hyperglycemia

Details Preventive or remedy for diseases caused by hyperglycemia Preventive or remedy for diseases caused by hyperglycemia

A - Human Necessities

61

K

A61K 31/706 (2006.01) A61K 31/7056 (2006.01) A61K 45/00 (2006.01) A61P 3/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2507665

It is intended to provide a medicinal composition containing as the active ingredient a selective SGLT1 inhibitor (for example, an SGLT1 inhibitor substantially showing no GLUT2 and/or GLUT5 inhibitory effect) which exerts a sugar absorption inhibitory effect over a wide range, also has a hypoglycemic effect caused by fructose intake in usual diet and thus can show an outstanding hypoglycemic effect and which is appropriate as a preventive or a remedy for diseases caused by hyperglycemia (for example, diabetes, impaired glucose tolerance, diabetic complications or obesity).

La présente invention a trait à une composition médicinale contenant en tant que principe actif un inhibiteur sélectif de SGLT1 (par exemple, un inhibiteur de SGLT1 ne présentant pas d'effet d'inhibition de GLUT2 et/ou de GLUT5) qui réalise un effet d'inhibition d'absorption de sucre de manière extensive, et a également un effet hypoglycémique dû à l'ingestion du fructose dans un régime classique et peut ainsi présenter un effet hypoglycémique considérable et est appropriée à la prévention ou au traitement de maladies causées par l'hyperglycémie (par exemple, le diabète, la tolérance déficiente du glucose, les complications diabétiques ou l'obésité).

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