Preventive or therapeutic agent for disease caused by...

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01) A61K 31/137 (2006.01) A61K 31/196 (2006.01) A61K 31/216 (2006.01) A61K 31/472 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2619445

It is intended to provide a preventive or therapeutic drug for a disease caused by a decrease in lacrimal fluid. More specifically, it is intended to provide a preventive or therapeutic drug for a disease caused by a decrease in lacrimal fluid (dry eye, dry keratoconjunctivitis, keratoconjunctival epithelial damage, a decrease in lacrimation, xerophthalmia, age-related dry eye syndrome, eye damage in Stevens-Johnson syndrome, eye damage in Sjogren syndrome, keratoconjunctival ulcer, dryness in wearing contact lenses or the like), characterized by containing a .beta.3-adrenergic receptor stimulant. Further, it is intended to provide a combination drug, characterized by containing the .beta.3-adrenergic receptor stimulant and a .beta.2-adrenergic receptor stimulant in combination.

L~invention concerne un médicament préventif ou thérapeutique pour une maladie causée par une baisse du liquide lacrymal. Plus particulièrement, l~invention permet d~obtenir un médicament préventif ou thérapeutique pour une maladie causée par une baisse du liquide lacrymal (AEil sec, kératoconjonctivite sèche, lésion épithéliale kératoconjonctivale, baisse du larmoiement, xérophtalmie, syndrome de l'AEil sec lié à l~âge, lésion de l'AEil dans le syndrome de Stevens-Johnson, lésion de l'AEil dans le syndrome de Sjogren, ulcère kératoconjonctival, sécheresse lors du port de verres de contact ou similaires), caractérisé en ce qu~il contient un stimulant du récepteur .beta.3-adrénergique. De plus, il s~agit d~un médicament de combinaison, caractérisé en ce qu~il contient un stimulant du récepteur .beta.3-adrénergique combiné à un stimulant du récepteur .beta.2-adrénergique.

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