Preventive or therapeutic agent for vascular intimal...

A - Human Necessities – 61 – K

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A61K 31/4035 (2006.01) A61K 45/00 (2006.01) A61P 9/10 (2006.01) C07D 209/44 (2006.01)

Patent

CA 2571822

A medicinal composition for the prevention or treatment of diseases attributable to vascular intimal proliferation, such as restricture after operations for coronary intervention. The medicinal composition for the prevention or treatment of diseases attributable to vascular intimal proliferation, such as restricture after operations for coronary intervention, contains as an active ingredient any of (2S)-2-benzyl-3-(cis-hexahydro-2- isoindolinylcarbonyl)~propionic acid, which is represented by the following formula (general name: mitiglinide), pharmacologically acceptable salts of the acid, and hydrates of these.

Composition médicale pour la prévention ou le traitement de maladies attribuées à la prolifération intimale vasculaire, telles que le rétrécissement après des opérations avec intervention coronarienne. Cette composition médicale pour la prévention ou le traitement de maladies imputables à la prolifération intimale vasculaire, telles que le rétrécissement après des opérations avec intervention coronarienne, contient comme ingrédient actif un acide propionique (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)­, qui est représenté par la formule suivante (nom générique : mitiglinide), sels acceptables de l~acide d~un point de vue pharmacologique, et de leurs hydrates.

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