Preventive or therapeutic medicines for diabetes containing...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61K 31/53 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 13/12 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2429067

Preventive or therapeutic medicines for diabetes, containing fused-heterocycle compounds of the general formula (I') or salts thereof as the active ingredient: (I') wherein G is CN, NO2, CO2R4, CHO, SO2NRaRb, or CONRaRb; R1 is halogeno, -O-R5, or S-R5; R2 is halogeno, -O-R5 (wherein R5 is as defined above), or optionally substituted amino; and R8 and R10 are each independently hydrogen, halogeno, or alkyl.

Cette invention se rapporte à des médicaments préventifs ou thérapeutiques contre le diabète, qui contiennent des composés à hétérocycle fusionné représentés par la formule générale (I') ou des sels de ces composés, comme principe actif. Dans ladite formule, G représente CN, NO¿2?, CO¿2?R?4¿, CHO, SO¿2?NR?a¿R?b¿ ou CON?a¿R?b¿; R?1¿ représente halogénure, -O-R?5¿ ou -S-R?5¿; R?2¿ représente halogéno, -O-R?5¿ (où R?5¿ est défini ci-dessus) ou un amino éventuellement substitué; et R?8¿ et R?10¿ représentent chacun séparément hydrogène, halogéno ou alkyle.

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