C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07K 16/18 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2551546
It is intended to provide a substance inhibiting the binding of a protein containing an amino acid sequence which is the same or substantially the same as an amino acid sequence represented by SEQ ID NO:1, SEQ ID NO:4, SEQ ID NO:7 or SEQ ID NO:10, its partial peptide or a salt thereof to a protein containing an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:26, its partial peptide or a salt thereof; and a preventive/remedy for cancer, an apoptosis promoter for cancer cells, a growth inhibitor for cancer cells and so on containing the above substance.
L'invention concerne une substance qui inhibe la liaison d'une protéine contenant une séquence d'acides aminés identique ou sensiblement identique à la séquence d'acides aminés représentée par SEQ ID NO:1, SEQ ID NO:4, SEQ ID NO:7 ou SEQ ID NO:10, le peptide partiel de ladite protéine ou son sel, à une protéine contenant une séquence d'acides aminés identique ou sensiblement identique à la séquence d'acides aminés représentée par SEQ ID NO:26, le peptide partiel de ladite protéine ou son sel. L'invention concerne une substance destinée à la prévention et au traitement du cancer; un promoteur d'apoptose de cellules cancéreuses; un inhibiteur de croissance de cellules cancéreuses, etc., contenant ladite substance.
Ishii Takafumi
Sunahara Eiji
Fetherstonhaugh & Co.
Takeda Pharmaceutical Company Limited
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