Primary biliary cirrhosis autoantigen

Details Primary biliary cirrhosis autoantigen Primary biliary cirrhosis autoantigen

C - Chemistry, Metallurgy

12

N

530/13, 167/44,

C12N 15/12 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/96 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341231

A synthetic peptide or polypeptide displaying the antigenicity of all or a portion of the 70kd mitochondrial autoantigen of primary biliary cirrhosis, or an antigenically active fragment thereof, is produced by recmbinant DNA techniques. The synthetic peptide or polypeptide, or fragment, may be used in the treatment of patients or in diagnostic tests, particularly for the detection of anti-mitochondrial antibody in a serum sample.

554320

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