Prime-boost vaccination strategy

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/165 (2006.01) A01H 5/00 (2006.01) A61K 48/00 (2006.01) C07K 14/12 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2402831

The present invention provides a method for inducing an immune response to an antigen in a subject. The method comprises administering to the subject DNA encoding the antigen, and subsequently orally administering to the subject a composition comprising transgenic material, wherein the transgenic material comprises a DNA molecule encoding the antigen such that the antigen is expressed in the transgenic material.

L'invention concerne un procédé permettant d'induire une réponse immune à un antigène chez un sujet. Ce procédé consiste à administrer au sujet un ADN codant pour cet antigène, puis à administrer au sujet, par voie orale, une composition contenant du matériel transgénique, ce matériel transgénique comprenant une molécule D'ADN codant pour l'antigène de sorte que cet antigène est exprimé dans le matériel transgénique.

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