Prime ring substituted thyroid receptor antagonists for the...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 277/04 (2006.01) A61K 31/085 (2006.01) A61K 31/192 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/603 (2006.01) C07C 53/122 (2006.01) C07C 53/132 (2006.01) C07C 53/134 (2006.01) C07C 59/68 (2006.01) C07C 65/26 (2006.01) C07D 213/04 (2006.01) C07D 213/30 (2006.01) C07D 241/04 (2006.01) C07D 241/12 (2006.01)

Patent

CA 2449515

This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism and liver diseases.

Cette invention concerne de nouveaux composés qui sont des ligands du récepteur de la thyroïde, de préférence des antagonistes, et des méthodes d'utilisation de ces composés dans le traitement de troubles cardiaques ou métaboliques, tels que l'arythmie cardiaque, la thyrotoxicose, l'hyperthyroïdie subclinique ou les maladies hépatiques.

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