Prion-binding activity in serum and proteins

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/705 (2006.01) A61K 35/66 (2006.01) A61K 35/76 (2006.01) A61P 25/28 (2006.01) C07K 14/75 (2006.01) C12N 9/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2413742

Disclosed are methods and tools for the concentration and detection as well as quantification of pathological prion proteins as well as agents to be used in said detection and/or in the prevention or treatment of prion diseases. Said agents are factors with prion binding activities found in blood serum and blood plasma.

L'invention concerne des procédés et des outils destinés à concentrer, à détecter et à quantifier des protéines prion pathologiques ainsi que des agents à utiliser dans ladite détection et/ou dans la prévention ou dans le traitement des maladies à prion. Ces agents sont des facteurs dotés d'activités de liaison au prion que l'on trouve dans le sérum sanguin et dans le plasma sanguin.

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