C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12P 21/00 (2006.01)
Patent
CA 2402787
Transgenic and cloned ungulates and particularly cloned cattle are disclosed, wherein such cattle contain a deletion or disruption of the prion gene locus and do not express functional prion protein, and are not susceptible to prion- related diseases such as bovine spongiform encephalopy or Mad Cow Disease.
L'invention concerne des ongulés clonés transgéniques, et notamment des bovins clonés présentant une délétion ou une disruption du locus du gène du prion. Ces bovins n'expriment pas la protéine fonctionnelle du prion et ne sont pas sujets aux maladies liées au prion, telles que l'encéphalopathie spongiforme bovine ou la maladie de la vache folle.
Cibelli Jose
Good Deborah J.
As Represented By Its Amherst Campus University Of Massachusetts A. Public Institution Of The Commonw
Gowling Lafleur Henderson Llp
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