Prion protein conversion assay, prion protein intermediate...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) C12Q 1/37 (2006.01) G01N 33/535 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2392997

The invention relates to a method of producing an intermediate prion protein comprising contacting a PrP c substrate with a low pH solution. The invention is useful in assays to detect prion conversion and prion diseases.

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