Prion-specific peptide reagents

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 35/14 (2006.01) A61K 38/17 (2006.01) C07K 1/22 (2006.01) C07K 17/00 (2006.01) C12N 15/12 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2535261

Peptide reagents that interact preferentially with the PrPsc form of the prion protein are described. Methods of using the reagents or antibodies to the reagents for detection, diagnosis, purification, therapy and prophylaxis for prions and prion-associated diseases are also described.

L'invention concerne des réactifs peptidiques interagissant de manière préférentielle avec la forme PrP?sc¿ de la protéine prion. L'invention concerne également des méthodes d'utilisation de ces réactifs ou d'anticorps auxdits réactifs dans la détection, le diagnostic, la purification, le traitement et la prévention des maladies à prions et des maladies liées aux prions.

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