C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A01K 67/027 (2006.01) C12N 9/12 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2474005
The invention provides an isolated human Prkag3 promoter. Expression constructs containing the Prkag3 promoter also are provided, as are methods of using such expression constructs to direct expression of a heterologous coding sequence. Host cells containing an expression construct of the invention are provided, as well as methods of using such cells to screen for compounds that transcriptionally modulate the activity of a Prkag3 promoter.
L'invention concerne un promoteur du gène Prkag3 humain isolé. L'invention concerne par ailleurs des produits d'expression contenant le promoteur de Prkag3 ainsi que des procédés d'utilisation de ces produits d'expression pour induire l'expression directe d'une séquence de codage hétérologue. De plus, l'invention concerne des cellules hôtes qui contiennent un produit d'expression de l'invention ainsi que des procédés d'utilisation de ce type de cellules pour cribler des composés qui modulent par voie transcriptionnelle l'activité d'un promoteur de Prkag3.
Svensson Thomas
Arexis Ab
Ridout & Maybee Llp
LandOfFree
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