Prkcs as modifiers of the beta catenin pathway and methods...

Details Prkcs as modifiers of the beta catenin pathway and methods... Prkcs as modifiers of the beta catenin pathway and methods...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 39/395 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2535812

Human PRKC genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PRKC are provided.

L'invention concerne des gènes PRKC humains identifiés comme modulateurs de la voie bêta caténine, constituant des cibles thérapeutiques pour les troubles liés à une fonction bêta caténine déficiente. L'invention concerne également des méthodes d'identification des modulateurs de la bêta caténine. Ces méthodes consistent à cribler des agents modulant l'activité des PRKC.

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