Pro-drugs of n-thiazol-2yl-benzamide derivatives

Details Pro-drugs of n-thiazol-2yl-benzamide derivatives Pro-drugs of n-thiazol-2yl-benzamide derivatives

C - Chemistry, Metallurgy

07

D

C07D 277/46 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2606011

The invention relates to compounds of the formula I wherein the variables are as defined in the claims. The compounds are pro-drugs of A2A-receptor ligands with improved aqueous solubility, and are useful in the treatment of neurological and psychiatric disorders where an A2A-receptor is implicated.

L'invention concerne des composés de formule I dans laquelle les variables sont telles que définies dans les revendications. Les composés sont des promédicaments de ligands du récepteur A2A ayant une meilleure solubilité dans l'eau et ils sont utiles dans le traitement de troubles neurologiques et psychiatriques dans lesquels le récepteur A2A est impliqué.

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