Proanthocyanidol composition and pharmacological use thereof

Details Proanthocyanidol composition and pharmacological use thereof Proanthocyanidol composition and pharmacological use thereof

C - Chemistry, Metallurgy

07

D

C07D 311/62 (2006.01) A61K 31/35 (2006.01) A61K 35/78 (1990.01)

Patent

CA 2057023

The invention relates to a proanthocyanidol-based composition, notably of vegetable origin, characterized by a weight ratio of at least 50 % in molecules having an apparent molecule weight greater than 2000, said proportion being made up of at least 40 % proanthocyanidols, their percentage being expressed as a tannate function, and by the fact that said composition is essentially free from aromatic essences, in particular essential oils, of resins and other lipophilic substances; of polymerized sugars such as starch, gums, and cellulose derivates; of oligomer sugars, such as saccharose, glucose, and fructose. The invention also relates to the use of said composition in pharmaceutical compositions.

2057023 9013304 PCTABS00102 L'invention concerne une composition à base de proanthocyanidols, notamment d'origine végétale, caractérisée par une proportion pondérale d'au moins 50 % de molécules ayant des poids moléculaires apparents supérieurs à 2000, cette proportion étant constituée d'au moins 40 % de proanthocyanidols, ce pourcentage étant exprimé en fonction tannante, et en ce que ladite composition est essentiellement exempte: d'essences aromatiques et notamment d'huiles essentielles, de résines et autres substances lipophiles; de sucres polymérisés tels que l'amidon, les gommes, les dérivés cellulosiques; de sucres oligomères tels que le saccharose, le glucose, le levulose. Elle vise aussi l'application de cette composition dans des compositions pharmaceutiques.

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