Probe for analysis of nucleic acids

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/00 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01) C09B 23/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2256545

The invention is a probe for detecting nucleic acids having a particular sequence. 1t is composed of two joint units. One unit is chemically different from natural nucleic acids, but has the ability to recognize a particular sequence of bases or base pairs in single or double-stranded DNA of RNA. The other unit is a compound whose detectable properties are altered upon binding to nucleic acids.

L'invention concerne une sonde pour la détection d'acides nucléiques ayant une séquence particulière. Elle se compose de deux unités jointes. Une unité est chimiquement différente des acides nucléiques naturels mais a la capacité de reconnaître une séquence particulière de bases ou de paires de bases dans l'ADN simple ou double brin de l'ARN. L'autre unité est un composé dont les propriétés détectables sont modifiées lors de la liaison aux acides nucléiques.

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