Probe system for performing hla dr typing and typing method...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2091775

Ensemble de sondes nucléotidiques permettant de déterminer selon les techniques usuelles de typage par oligonucléotides, les types HLA DR et/ou sous types associés, ledit ensemble de sondes comprenant au moins les sondes nucléotidiques formule (I), (la partie soulignée correspondant à la séquence optimum), lesdites sondes pouvant être sous forme marquée, ou couplées de façon covalente â un ligand facilitant leur fixation sur un support solide, ou fixées sur un support solide. Utilisation de ces sondes dans un procédé de typage HLA DR, par exemple comme sondes de capture selon la technique sandwich.

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