Probes for detecting mutant p53

Details Probes for detecting mutant p53 Probes for detecting mutant p53

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C07K 16/32 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2064555

2064555 9200311 PCTABS00010 A panel of probes detects and distinguishes between sets of human p53 gene or protein mutations that frequently occur or are selected for in pre-cancer and cancer cells. Each set gives rise to a phenotype that is different from that of wild-type p53 and of at least one other set of p53 mutants.

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