C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/10 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2283058
The invention relates to a method for diagnosing an HIV infection by means of an immunoassay specifically detecting p24 antigen of HIV1, HIV1-subO and/or p26 antigen of HIV2, at least one antibody against the env range of HIV1, HIV1- subO and/or HIV2 and at least one antibody against the pol and/or gag range from HIV1, HIV1-subO and/or HIV2. The invention further relates to reagent kits and test strips suitable for said diagnosis method, and to monoclonal antibodies against p24 and the use thereof.
L'invention concerne un procédé permettant de diagnostiquer une infection par VIH, par mise en évidence spécifique de l'antigène p24 du VIH1, VIH1-SubO et/ou de l'antigène p26 du VIH2, d'au moins un anticorps agissant à l'encontre de la zone env du VIH1, VIH1-SubO et/ou du VIH2 et d'au moins un anticorps agissant à l'encontre de la zone pol et/ou gag provenant du VHI1, VIH1-SubO et/ou du VIH2. L'invention concerne en outre des kits de réactifs et des bandelettes de test appropriés audit procédé de diagnostic, ainsi que des anticorps monoclonaux agissant à l'encontre du p24 et leur utilisation.
Buyse Marie-Ange
Donie Frederic
Faatz Elke
Hoess Eva
Saman Eric
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Roche Diagnostics Gmbh
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