Procedure for the detection of high virus concentrations in...

C - Chemistry – Metallurgy – 12 – Q

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12Q 1/70 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2252013

A procedure for the detection of high virus concentrations in blood plasma and/or blood serum by means of the polymerase chain reaction (PCR) is described, in which the sensitivity of the PCR is restricted by the use of suboptimal nucleic acid extraction, amplification or detection conditions. This procedure is suitable, for example, for the detection of parvovirus DNA in plasma or serum, it being possible to adjust the sensitivity of the PCR such that the parvovirus DNA is only detected in samples whose DNA content is greater than 10 6 to 10 7 genome equivalents/ml. The detection of the parvovirus DNA amplification carried out is carried out in the sample by measurements of the fluorescence.

Dans l'invention, on décrit un procédé permettant de détecter des concentrations très élevées de virus dans le plasma et/ou le sérum sanguin au moyen de la réaction en chaîne de la polymérase (PCR), dans lequel la sensibilité de la PCR est limitée par le recours à des conditions d'extraction, d'amplification ou de détection d'acides nucléiques sous-optimales. Le procédé convient, par exemple, à la détection de l'ADN de parvovirus dans le plasma ou le sérum. Il est possible d'ajuster la sensibilité de la PCR de sorte que l'ADN de parvovirus n'est détecté que dans les échantillons dont la quantité d'ADN est supérieure à 106 to 107 équivalents de génome par ml. La détection de l'ADN de parvovirus amplifié est réalisée dans l'échantillon à l'aide d'une mesure de la fluorescence.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Procedure for the detection of high virus concentrations in... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Procedure for the detection of high virus concentrations in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Procedure for the detection of high virus concentrations in... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1612139

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.