Process

Details Process Process

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) C07D 215/233 (2006.01) C07D 215/56 (2006.01) C07D 491/056 (2006.01) C07F 7/22 (2006.01)

Patent

CA 2047249

ABSTRACT PROCESS The invention provides a novel process for the manufacture of quinoline derivatives of the formula III as defined hereinafter which are angiotensin II inhibitors. The process involves the removal of a trisubstituted tin moiety from a compound of the formula IV, in which R1, R2, R3, R4, R5, Ra, Rb and Q have the various meanings defined hereinafter. Certain of the intermediates are novel and are provided as a further feature of the invention.

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