C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/04 (2006.01)
Patent
CA 2408853
A process in which a salt of clavulanic acid, typically an amine salt or an alkali metal salt is exposed to conditions, particularly a pH of less than 6.0, which reduces the quantity of contaminating impurities. The process may be a washing process, a recrystallisation process or a preparative process.
L'invention concerne un procédé dans lequel un sel d'acide clavulanique, généralement un sel d'amine ou un sel de métal alcalin, est exposé à certaines conditions, en particulier un pH inférieur à 6,0, ce qui permet de réduire la quantité d'impuretés contaminantes. Ce procédé peut être un procédé de lavage, un procédé de recristallisation ou un procédé de préparation.
Mcknight John
Zhang Guo
Gowling Lafleur Henderson Llp
Smithkline Beecham P.l.c.
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