C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2269865
The present invention concerns in particular a process intended to evidence the state of a malignant cell, wherein the specific appearance of at least one gene within the nucleus of said cell is evidenced by labelling said gene in situ and evaluating the deviation in its appearance with respect to a normal cell as an indication of the malignancy of the cell tested. Reorganization genes are useful in the treatment of certain anticancer processes.
La présente invention concerne notamment un procédé destiné à mettre en évidence l'état d'une cellule maligne, dans lequel on met en évidence la conformation précise d'au moins un gène au sein du noyau de ladite cellule par marquage dudit gène in situ et évaluation de l'écart de ladite conformation par rapport à une cellule normale comme index de la malignité de la cellule testée. Des gènes de réorganisation sont utiles dans le traitement de certains processus anticancéreux.
Calvo Fabien
Molecular Engines Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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