Process and a reagent for the removal of turbidities

G - Physics – 01 – N

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150/1, 134/43

G01N 33/52 (2006.01) C12Q 1/54 (2006.01) C12Q 1/60 (2006.01) C12Q 1/62 (2006.01) G01N 1/34 (2006.01) G01N 33/96 (2006.01) G01N 33/04 (2006.01)

Patent

CA 1131097

-1 - ABSTRACT For the removal of turbidities in reaction mixtures clouded by sample material, especially for photometric measurement, there are added to the reaction mixture: a) at least one low molecular weight organic compound, such as an aromatic alcohol or amine, which contains an electronegative substituent, for example a phenol or naphthol, which is substituted with one or more halogen atoms and/or hydroxyl groups and b) at least one detergent which dissolves without compound a) to give a clear solution and which forms a sparingly soluble complex with component a), such as a non-ionic poly- ethylene oxide adduct or a cationic detergent, especially an alkyl, aralkyl or alkylthio ether or an alkyl or aralkyl ester of a polyethylene oxide glycol containing 8 to 22 carbon atoms in the alkyl radical and 5 to 25 ethylene oxide units or an alkyl dimethyl benzyl ammonium chloride compound containing 8 to 22 carbon atoms in the alkyl radical, in an amount sufficient for the appearance of a precip- itate of the complex, whereafter further detergent is added thereto until the precipitated complex dissolves again.

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