A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/135
A61K 39/102 (2006.01)
Patent
CA 1189790
Abstract of the invention In an improved method for combating pleuropneumonia in pigs by administering a vaccine comprising cells of the known and generally available microorganism Haemophilus pleuropneumoniae, parts of such cells, extracts and/or me tabolism products thereof as the active ingredient, adjuvants and a buffer, the improvement consisting in the use of a sor- detella pertussis vaccine, biomass and/or extracts thereof as adjuvant, as well as the new H. pleuropneumoniae vaccine comprising a B. pertussis based adjuvant. The method and the vaccine result in an improved protection of the pigs against pleuropneumonia attacks without side-effects. Be- sides, a new and improved substrate called CAY-substrate for the cultivation of microorganisms, in particular the bacterium H. pleuropneumoniae, which compared to known sub- strates results in a substantially higher yield of biomass suitable for the production of a H. pleuropneumoniae vac- cine, said substrate comprising casamino acid, yeast ex- tract, glucose and NAD as essential ingredients and being suitable for cultivation of H. pleuropneumoniae on solid as well as in liquid media by slight modifications in the composition of the substrate An improved process for the aerobic fermentation of H. pleuropneumoniae in a liquid medium comprising the new CAY-substrate, the fermentation being advantageously performed at a temperature of about 37°C., a pH of about 7.1 to 7.4, and at an oxygen concen- tration in the fermentation medium of about 8 to 12 ppm, thereby maintaining the desired oxygen concentration by variation of the stirring speed and/or of the air flow rate.
355852
Fogh Joergen
Nielsen Bjarne
Riising Hans-Joergen
Nordisk Droge & Kemikalie A/s (northern Drugs & Chemicals Ltd.)
Ogilvy Renault
LandOfFree
Process and a substrate for the aerobic fermentation of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process and a substrate for the aerobic fermentation of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process and a substrate for the aerobic fermentation of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1205564