Process and apparatus for production of bi-213 cations

G - Physics – 21 – G

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G21G 4/08 (2006.01) A61K 51/00 (2006.01) A61K 51/12 (2006.01) C01G 29/00 (2006.01) G21F 9/00 (2006.01) G21F 9/12 (2006.01)

Patent

CA 2292621

A process for producing substantially impurity-free Bi-213 cations is disclosed. An aqueous acid feed solution containing Ac-225 cations is contacted with an ion exchange medium to bind the Ac-225 cations and form an Ac-225-laden ion exchange medium. The bound Ac-225 incubates on the ion exchange medium to form Bi-213 cations by radioactive decay. The Bi-213 cations are then recovered from the Ac-225-laden ion exchange medium to form a substantially impurity-free aqueous Bi-213 cation acid solution. An apparatus for carrying out this process is also disclosed.

L'invention porte sur un procédé de production de cations de Bi-213 sensiblement exempts d'impuretés. Une solution d'apport contenant des cations de Ac-225 est mise en contact avec un milieu échangeur d'ions se fixant aux cations de Ac-225 de manière à former un milieu échangeur d'ions chargé en Ac-225. Le Ac-225 fixé se transforme dans le milieu échangeur d'ions en donnant du Bi-213 par désintégration radioactive. Les cations de Bi-213 sont ensuite extraits du susdit milieu, ce qui laisse une solution acide de cations de Bi-213 sensiblement exempts d'impuretés. L'invention porte également sur un appareil d'exécution dudit procédé.

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