B - Operations – Transporting – 01 – D
Patent
B - Operations, Transporting
01
D
B01D 25/00 (2006.01) A61L 2/00 (2006.01) B01D 61/14 (2006.01) B01D 61/18 (2006.01) B01D 63/08 (2006.01)
Patent
CA 2121236
ABSTRACT OF THE DISCLOSURE A process for the removal of DNA, endotoxins and viruses from aqueous buffer solutions, aqueous pharmaceutical solutions and aqueous biological pharmaceutical solutions comprises passing one of above solutions through a single filtration device with two sections containing coated filter membranes and absolute pore filters. The filter device is capable of removing up to about 98% of the endotoxins in addition to removing viruses with an efficiency of at least 4.6 x 105 and DNA to less than 10 picograms per 500 mg sample.
Butchko Gregory
Glenn Stephan D.
O'connell Edward
Smariga Paulette
Coulter Corporation
Jarzyna Andrew K.
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