Process and apparatus for utilization of in vivo extracted...

A - Human Necessities – 61 – M

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A61M 1/16 (2006.01) A61M 1/34 (2006.01) A61M 1/36 (2006.01)

Patent

CA 2446580

The present invention is directed to a method of treating cells, tissues or organs using in vivo plasma separation by implanting a plasma separation filter device (1) within a blood vessel of a patient, or allogenic, or xenogenic donor, continuously separating blood plasma from whole blood in vivo, directing the plasma from the plasma separation filter device (1) to a bioreactor (15), and exposing the plasma to cells, tissue or an organ within the bioreactor utilizing immune separation membranes where necessary.

L'invention concerne un procédé de traitement de cellules, de tissus ou d'organes, qui utilise une séparation in vivo de plasma et comprend les étapes consistant à : mettre en place un dispositif filtre (1) de séparation de plasma dans le vaisseau sanguin d'un patient, ou d'un donneur allogène ou xénogène ; séparer en continu le plasma sanguin du sang entier in vivo ; diriger le plasma du dispositif filtre de séparation (1) de plasma vers un bioréacteur (15); et exposer le plasma à des cellules, à un tissu ou à un organe dans le bioréacteur, à l'aide de membranes barrières immunitaires de séparation si nécessaire.

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