G - Physics – 01 – N
Patent
G - Physics
01
N
167/139, 167/37
G01N 33/48 (2006.01) A61K 37/00 (1980.01)
Patent
CA 1062609
ABSTRACT OF THE DISCLOSURE A method, composition and test kit are provided for determination of CK-MB activity in a sample of biological liquids. The method comprises the steps of incubating the sample, optionally in the presence of CK substrates, with antibodies which inhibit enzymatic activity of the M subunit in CX isoenzymes MM and MB without substantially inactivating enzymatic activity of the B subunit in any CK-MB which may be present, and then determining the activity of the CK B subunit in the resultant sample. This provides a simple, rapid and reproducible method for the diagnosis of cardiac infarction.
264720
Hennrich Norbert
Lang Hermann
Orth Hans-Dieter
Wurzburg Uwe
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