Process and device for encapsulating a substance

B - Operations – Transporting – 01 – J

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B01J 2/02 (2006.01) A61K 9/50 (2006.01) B01J 13/04 (2006.01) C12N 5/00 (2006.01) C12N 11/04 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2117310

Encapsulation process of the type consisting in causing a substance to be encapsulated to flow within a capillary tube (1), extruding the substance from the tube and axially co-extruding a polymer substance at the circumference of said tube for encapsulation of the substance. The process also consists in segmenting, by means of a vector fluid, the flow of the substance to be encapsulated prior to its extrusion, lowering the temperature of the formed capsule, and then exchanging the solvent contained in the polymer solution for a non-solvent. The invention also concerns a device for carrying out the process of the invention.

2117310 9408569 PCTABS00166 La présente invention a pour objet un procédé d'encapsulation du type consistant: à provoquer l'écoulement de la substance à encapsuler à l'intérieur d'un conduit capillaire (1), à extruder ladite substance à partir dudit conduit, à coextruder axialement une solution polymère en périphérie dudit conduit afin d'encapsuler la substance, qui consiste en outre : à segmenter par un fluide vecteur le flux de substance à encapsuler préalablement à son extrusion, à abaisser la température de la capsule formée, puis à échanger le solvant contenu dans la solution polymère par un non solvant. L'invention a également pour objet un dispositif permettant la mise en oeuvre du procédé de l'invention.

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