Process and device for producing liquid dosage formulations

B - Operations – Transporting – 01 – F

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Details

B01F 3/12 (2006.01) A61J 3/00 (2006.01) A61K 9/00 (2006.01) B01F 7/16 (2006.01) B01F 13/00 (2006.01) B01F 15/00 (2006.01)

Patent

CA 2407335

The invention relates to a process and device for making liquid dosage formulations from solid dosage forms, and the pharmaceutical compositions produced therefrom. The device comprises a mixing and dosing cup having an abrasive interior surface and may include a mixing blade attached to an external motor. According to the process, a liquid dosage formulation is prepared by combining a solid dosage form of a pharmaceutical medicament and an aqueous diluent in the mixing and dosing cup, agitating the resultant mixture, and administering the resulting liquid dosage formulation to a patient in the mixing and dosing cup.

Cette invention se rapporte à un procédé et à un dispositif servant à produire des formulations posologiques liquides à partir de formes posologiques solides, et aux compositions pharmaceutiques ainsi produites. Ce dispositif comprend un récipient mélangeur et doseur ayant une surface intérieure abrasive et il peut contenir une lame mélangeuse fixée à un moteur externe. Selon ce procédé, on prépare une formulation posologique liquide en combinant une forme posologique solide d'un médicament pharmaceutique et un diluant aqueux dans le récipient mélangeur et doseur, en agitant le mélange qui en résulte, et en administrant la formulation posologique liquide qui en résulte à un patient dans le récipient mélangeur doseur.

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