Process and device for separating and testing whole blood

Details Process and device for separating and testing whole blood Process and device for separating and testing whole blood

C - Chemistry, Metallurgy

12

Q

150/11, 167/114

C12Q 1/56 (2006.01) A61M 1/34 (2006.01) G01N 33/50 (2006.01) G01N 33/52 (2006.01) G01N 33/70 (2006.01) G01N 33/72 (2006.01)

Patent

CA 1310905

PROCESS AND DEVICE FOR SEPARATING AND TESTING WHOLE BLOOD ABSTRACT OF THE DISCLOSURE A process and device for separating plasma or serum from whole blood. The device includes one or more bibulous matrices, treated to separate the serum or plasma from the cellular components of whole blood. In one embodiment of the inven- tion, the separated, undiluted soluble constitu- ents (plasma or serum) from the whole blood sample can then can be analyzed for a particular soluble constituent. The process includes depositing the whole blood on a treated bibulous matrix containing a nonblood specific lectin, a thrombin or mixture thereof, whereby the cellular compon- ents are separated from the whole blood as it permeates through the bibulous matrix. The essen- tially cell-free plasma or serum then passes to an assay area of the same, or an adjacent, bibu- lous matrix for detection of a particular soluble constituent of whole blood. MS-1469

566515

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