Process and intermediates for preparing 5-lipoxygenase...

Details Process and intermediates for preparing 5-lipoxygenase... Process and intermediates for preparing 5-lipoxygenase...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) C07D 309/08 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2289422

The present invention relates to the process for preparing a compound of the formula (see formula I) wherein A is C1-C6 alkyl, an aryl which is mono or disubstituted with F, Cl , Br,, OCH3, C1-C3 alkyl or benzy. In the preferred compound A is CH3. The 5-lipoxygenase inhibitors that are prepared in accordance with the present invention are selective inhibitors of the action of lipoxygenase enzyme and are useful in the treatment or alleviation of inflammatory diseases, allergy and cardiovascular diseases in mammals.

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