Process and intermediates for preparing arzoxifene

C - Chemistry – Metallurgy – 07 – D

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C07D 333/64 (2006.01)

Patent

CA 2681478

The present invention provides for novel compounds of formula I wherein X is S or S(O); R1 and R2 are each independently selected from the group consisting of -CH2CH3 and phenyl; or R1 and R2 combine to form morpholino; and processes to prepare arzoxifene.

L'invention concerne de nouveaux composés représentés par la formule (I) dans laquelle X représente S ou S(O); R1 et R2 sont chacun sélectionnés indépendamment dans le groupe constitué par -CH2CH3 et phényle; ou R1 et R2 se combinent pour former morpholino. L'invention concerne également des procédés pour préparer l'arzoxifène.

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