Process and intermediates for the preparation of pyrrolidine...

Details Process and intermediates for the preparation of pyrrolidine... Process and intermediates for the preparation of pyrrolidine...

C - Chemistry, Metallurgy

07

D

C07D 207/16 (2006.01)

Patent

CA 2521487

A novel process is provided for the preparation of pyrrolidine carboxylic acids, and the useful intermediates obtained therein. These compounds are intermediates for the synthesis of melanocortin-4 receptor (MC-4R), which are useful for the treatment of disorders such as obesity, diabetes, male sexual dysfunction, and female sexual dysfunction.

Cette invention se rapporte à un nouveau procédé servant à la préparation d'acides carboxyliques de pyrrolidine, ainsi qu'aux intermédiaires utiles obtenus dans ce procédé. Ces composés constituent des intermédiaires pour la synthèse du récepteur de mélanocortine-4 (MC-4R), qui sont utiles dans le traitement des troubles tels que l'obésité, le diabète, les dysfonctionnements sexuels chez l'homme et les dysfonctionnements sexuels chez la femme.

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