Process and intermediates for the synthesis of caspofungin

Details Process and intermediates for the synthesis of caspofungin Process and intermediates for the synthesis of caspofungin

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) C07K 1/113 (2006.01)

Patent

CA 2626921

The present invention relates to novel processes for preparing certain aza cyclohexapeptide compounds, e.g. caspofungin, novel intermediates used in said processes and a process for preparing said intermediates. In particular, the intermediates have formula (II), wherein X is amino or substituted amino, and contains a cyano/nitrile functionality.

La présente invention concerne des procédés innovants pour la préparation de certains composés d'aza cyclohexapeptide, par exemple la caspofungine, des intermédiaires innovants utilisés dans lesdits procédés et un procédé de préparation desdits intermédiaires. En particulier, les intermédiaires ont la formule (II), dans laquelle X est un amino ou un amino substitué et contient une fonction cyano/nitrile.

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