Process and reagent for the determination of fibrin monomer...

Details Process and reagent for the determination of fibrin monomer... Process and reagent for the determination of fibrin monomer...

C - Chemistry, Metallurgy

12

Q

150/14, 150/3

C12Q 1/56 (2006.01)

Patent

CA 1248433

ABSTRACT Process and reagent for the determination of fibrin monomer in plasma The present invention provides a process for the determination of fibrin monomer in plasma, wherein a plasma sample containing fibrin monomer and freed from plasmin inhibitors is incubated in buffered solution with tissue plasminogen activator (EPA), plasminogen and a chromogenic plasmin substrate and the colour formed is measured as a measure of the amount of fibrin monomer. The present invention also provides a reagent for the determination of fibrin monomer in plasma, wherein it contains plasminogen, tissue plasminogen activator (EPA), chromogenic plasmin substrate and buffer (pH 7.0 to 9.0).

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