G - Physics – 01 – N
Patent
G - Physics
01
N
167/45
G01N 33/573 (2006.01) G01N 33/577 (2006.01) C07K 15/00 (1990.01)
Patent
CA 1277231
ABSTRACT Process and reagent for the specific determination of pancreatic .alpha.-amylase The present invention provides a process for the specific determination of pancreatic .alpha.-amylase in the presence of salivary .alpha.-amylase in body fluids, espec- ially in serum plasma, duodenal juices or urine, by reaction with a system for the detection of .alpha.-amylase in the presence of a monoclonal antibody which reacts with salivary .alpha.-amylase, wherein a monoclonal antibody is used which specially inhibits the salivary enzyme but does not inhibit the pancreatic enzyme by more than 50%. The present invention also provides a reagent for the specific determination of pancreatic .alpha.-amylase in the presence of salivary .alpha.-amylase in body fluids, especially in serum, plasma, duodenal juices or urine, comprising a system for the detection of .alpha.-amylase and a monoclonal antibody against salivary .alpha.-amylase, wherein it contains a monoclonal antibody which spec- ifically inhibits the salivary enzyme but does not inhibit the pancreatic enzyme by more than 50%.
499237
Gerber Martin
Naujoks Kurt
Wulff Karl
Boehringer Mannheim Gmbh
Gerber Martin
Naujoks Kurt
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Wulff Karl
LandOfFree
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