Process for altering the host range of bacillus...

Details Process for altering the host range of bacillus... Process for altering the host range of bacillus...

C - Chemistry, Metallurgy

12

N

530/13, 167/5.1,

C12N 15/31 (2006.01) A01N 63/00 (2006.01) A01N 63/02 (2006.01) C07K 14/325 (2006.01) C12N 1/20 (2006.01)

Patent

CA 1341092

The invention concerns an in vitro process for altering the insect host range (spectrum) of pesticidal toxins. The process comprises recombining in vitro the variable region(s) (non-homologous) of two or more genes encoding a pesticidal toxin. Specifically exemplified is the recombining of the variable regions of two genes obtained from well-known strains of Bacillus thuringiensis var. kurstaki. The resulting products are chimeric toxins which are shown to have an expanded and/or amplified insect host range as compared to the parent toxins.

520375

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