Process for antimicrobial treatment of polyurethane

Details Process for antimicrobial treatment of polyurethane Process for antimicrobial treatment of polyurethane

A - Human Necessities

61

L

A61L 2/16 (2006.01) A01N 33/12 (2006.01) A61L 15/26 (2006.01) A61L 15/46 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 31/06 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2068168

ABSTRACT OF THE DISCLOSURE PROCESS FOR ANTIMICROBIAL TREATMENT OF POLYURETHANE The present invention is directed to a method for impregnating a preformed polyurethane medical device with an antimicrobial quaternary ammonium compound which comprises the steps of (A) contacting said device with a solution containing said compound in a chlorinated or fluorinated hydrocarbon solvent thereby impregnating the device, and (B) removing the solvent, wherein the antimicrobial quaternary ammonium compound is represented by Formula (I) (I) Image including optically active isomeric forms thereof, wherein (a) R1, R2, R3, and R4 are independently selected from the group consisting of straight- or branched-chain, saturated or unsaturated alkyl groups having from 1 to 20 carbon atoms, or (b) R1, R2, and R3 are as defined above and R4 is selected from the group consisting of aryl alkyl, chloroaryl alkyl, aryloxy alkyl, and trialkyl ammonium alkyl, or (c) R1 and R2 are as defined above and R3 and R4 are independently selected from the group consisting of aryl alkyl, monoalkylaryloxy alkyleneoxy alkyl, and dialkylaryloxy alkyleneoxy alkyl, or (d) R1 is as defined above and R2, R3, R4, and the nitrogen atom are members of a heterocyclic ring, and X- is a halogen

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