Process for aqueous granulation of clarithromycin

Details Process for aqueous granulation of clarithromycin Process for aqueous granulation of clarithromycin

B - Operations, Transporting

01

J

B01J 2/00 (2006.01) A61K 9/16 (2006.01) A61K 47/32 (2006.01) A61K 31/71 (1995.01)

Patent

CA 2235607

The prevent invention provides a process for the aqueous granulation of a macrolide antibiotic which comprises mixing a macrolide antibiotic and a carbomer; wetting the mixture with water; and blending the mixture to allow formation of a macrolide antibiotic-carbomer granule.

L'invention concerne un procédé de granulation aqueuse d'un antibiotique de la famille des macrolides, qui comprend les étapes consistant à mélanger le macrolide avec un carbomère, puis à mouiller le mélange obtenu avec de l'eau et à mélanger le tout pour former des granules de macrolide-carbomère.

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